Prevention vs. Personalized Medicine: Obama Care is the backwards furture of medical care.

for the 1,000th time, STOP over-eating

Obama Care Will Spend Trillions to tell people what they already know: eat right, exercise and don't light up

Mr. Obama has found a woman to peddle: Laura. Obama likes to talk about Laura, a breast cancer survivor he met at a recent Town Hall Meeting; Laura is fighting a recurrence of the disease. Obama encouraged his team, as the debate for health care reform heats up this summer, “Every single day, I want you to remember Laura. Remember that’s who we’re here to serve and that’s who we’re looking out for.”

Now let’s talk about what works in breast cancer treatment; what is helping women to survive, what the future of advanced medicine is going to be about: personalized medicine. Sorry kids but if we are going to beat cancer this is pretty much the way it will be done.

Some background:
From HealthCentral.com:

Breast cancer was one of the earliest cancers to have this personalized touch through the works of pioneers in cell biology, researchers (such as the eminent Sir Craig V Jordan, formerly at Northwestern and now at Fox Chase) and most importantly patients.

Every breast cancer patient has her cancer tested for estrogen receptor, progesterone receptor, and Her2 status - Her2 being the latest addition to the personalized medicine armamentarium and arising in just the past ten years.

We know that medicines such as tamoxifen and the aromatase inhibitors work only in women with estrogen positive breast cancers, and that Herceptin only works in Her2+ breast cancers. We have personalized breast cancer treatment in terms of offering therapy for each woman that will give her the greatest chance of cure - or in the metastatic setting the greatest chance of response and durable remission.

And new work in breast cancer personalized medicine is being unearthed every day:

For example: this week from Reuters:

WASHINGTON (Reuters) – Genetic mutations can show which breast cancer patients will be helped by a certain type of chemotherapy, U.S. researchers reported on Tuesday.
They found patients with two versions of the SOD2 fared worse when taking the chemotherapy drug cyclophosphamide than other patients. It might be useful to test patients for this gene before giving them the drug, the researchers reported in the journal Clinical Cancer Research.
"In the future, such tests may be used to guide the treatment of patients with the SOD2 variation, ensuring that they receive a therapy that is more effective than cyclophosphamide-based therapies," Dr. Stefan Ambs of the National Cancer Institute, who worked on the study, said in a statement.

And its not just breast cancer, from HealthCentral.com

Personalized medicine is about to get more interesting. If one looks at choices of therapy in colon cancer, for example, we now know that one drug will work only in patients who have a "wild type K-ras" meaning that a protein involved in the cell cycle division process (dividing into two new cancer cells) must be preserved in structure for the drug to work. This is the biologic equivalent of stealth bombing.

These targets will arise in breast cancer as well since all cancer cells have similar biologic molecules involved in their unfettered cell division. A recent paper alluded to the higher probability of response with Bevacizumab based treatment, a targeted therapy against a molecule called vascular endothelial growth factor, in patients who have certain receptors for this molecule. Whereas now treatment is often empiric, we are moving towards the more specific.

Gene chip microarray technology - looking at genes expressed - will be utilized more in the future, as will its cousin proteonomics - assaying which proteins are expressed. What will this mean for the patients? It will hopefully mean better targeted therapies, with higher chances of working, and with less toxicity.
Science marches on!

Or, not!

Obama health care will focus on prevention over new and improved treatments.
Laura may have no way of preventing her cancer, but too bad for her.

Don’t eat those 10 bags of potato chips for lunch will be preferentially funded over personalized tumor treatments…the very treatments that are extending the lives of women who, by the un-luck of the draw, get breast cancer. (There has been a link between obesity and breast cancer, but this is not a strong link, and in no way accounts for the majority of breast cancer cases.)
Prevention preferences aside:

Mr. Obama is spending hundreds of billions of dollars to do meat and potato studies of current therapies, say, does physical therapy work better than arthroscopic surgery. The studies Mr. Obama is pushing are moving us away from personalized medicine and high-tech personalized advancements in cancer treatments and towards collective medicine.

Yes, with the Obama plan more people may get care, but that care will not be the care that sets the U.S. apart from the rest of the world. It will be collective care. It WILL be Heavily rationed care; it will weight prevention more heavily than advanced treatments. And when you are trying to stay alive this is important!

The will be much less money to fund the research that allows science to march on, so it will be backwards care rather than forwards care. Gadzillions of dollars will go towards telling people who are not going to change their behaviors to change their behaviors, rather than actually curing disease.

For example: boatloads of money will be go to pay doctors to spend hours lecturing patients not to stuff undue amounts of food into their faces and to get off their duffs and take the stairs.

I hate to break it to all those who talk about the HOLY DAY when doctors are paid well to lecture patients to eat right and exercise—it won’t make a difference.*
The only way to get people to do this is already proven: A good solid education.
College educated folks are far more likely to do the right thing. And btw, almost every community and hospital has wellness lectures, given by well-paid nurses. Do we REALLY want our extremely educated MDs to fritter away their brains telling patients to eat right and exercise? Trust me-- that can be delegated to nutritionists and nurses, as is currently the case! And it is REALLY boring to tell Sue and Derick for the bazillionth time, to stop already with the Fried Chicken.

One sure-fire way to lower health care costs via prevention: get women to earn a college degree before they make babies.
Well -educated mothers have less children and the children they do have will be far far less likely to end up as obese, smokers who are allergic to physical exercise. Over-eating smokers who drink too much and don’t exercise most often fall into lower socio-economic groups. This is a poverty thing that will not be answered by constant well-paid lectures by MDs to recalcitrant patients.
But this is where Mr. Obama is going to force our medical dollars. There are MANY good ways to reform health care, but penalizing those who do get sick is NOT one of them. Prevention sounds just great until... you get sick and then you just want to get better. I wonder if we will pay teams of I Told YOU SO doctors to march into patient sick rooms? Prevention with a Bite!

Prevention is being heavily touted up by the media and Mr. Obama. And this sounds just great to many folks. Currently “More than three-quarters of Americans (76 percent) support increasing funding for prevention programs that provide people with information and resources and creating policies that help people make healthier choices.” Source: Trust for America's Health

But wait until those same people get sick and are told that all the money that would have gone toward a personalized approach to their illness, is being pumped into repeatedly telling Americans what they knew in the first place: eat right and exercise. You will live a lot less longer, so that a lot more people can be told to eat right and exercise...over and over and over again.

Prevention will only save us money if people actually eat right and exercise and stop smoking. And all those prevention tests will cost boatloads of buck, and just about everyone in the medical know, knows that cost savings from preventative medicine will not materialze.

Obama himself can’t kick the smoking habit, most likely b/c of a genetic susceptibility to addiction. But rather than finding gene targets to hit with new compounds or treatments that will enable him to stand a chance at quitting, Obama doctors will be paid handsomely to tell him another 100 times: Hey man, you really should quit smoking!
Prevention has severe limits, both socioeconomically and genetically--neither of which will be fixed by spending all our health care bucks on lectures to recalcitrant patients.

So back to poor Laura: she may be a non-smoking, moderate drinking, vegetarian, who exercises and maintain her ideal body weight, but with Obama Care, Laura will not live as long. Personalized medicine will peter out...
but hey…. thousands of overweight obese folks will get weekly lectures and wrist slaps over their un-ending tendency to deep fry their Oreos.

*it is a no-brainer to advance the pay of primary care MDs. this is a simple act that would do much to reform health care w/o hurting the sick and retarding medical progress.

Comments

why can't reform be a private

why can't reform be a private plan that allows individuals to buy insurance at rates comparable to what is paid by employers.
Full cost of my cobra is $400 a month. If i try to buy comparable insurance as individual it is $800 a month for bare bones coverage. This would be great to have a govt. get private insurance to agree to a collective rate for single buyers.

That is reform I could get behind. Goverment run health care for all freaks me out. Medicare and Medicaid are flat broke, so how will we afford health care for the whole population. It will be no, no and no far more than we hear now!

I just ate lunch in the conf.

I just ate lunch in the conf. room watching TV monitor of a CNN medical correspondent telling patients to lie to medical staff in the ER to get faster care.

A woman named Cohen (can't recall her 1st name) told viewers to tell the triage RN to say things like: "my wife doesn't normally act this way" or that "her condition has worsended during the wait."

Implicit in this was the understanding that these would be lies, told to lessen the wait. CNN is openly suggesting that you lie about your medical condition to ER staff.
OK, so what does this mean: this means that those who have been professionally assessed as in greater need of care than you will have to wait longer for their care while you play games with the ER staff.

So that you can get meds for a migraine, a person with a potential brain bleed who failed to lie to the staff will be pushed back. AND even worse! If you tell medical staff of say odd behavioral changes (that are in fact not present) most likely you will get unneccessary tests that will cost taxpayers a whole boatload of bucks.
So suddenly a typical migrane that you simply need meds for becomes a full-on neuro work up!

This is why Hacks at CNN should not be allowed to shill for health care reform. They are not honest brokers!
SHAME on CNN.

BTW, they also recommended you lie and say you know the CEO of the hospital. Good one! Now as to that patient with arterial insuffiency on the way to a stroke or the guy whose abdominal aorta is about to dissect too bad for them. Wait for you care, whilst I lie like CNN told me to.

ughgha! what happened to responsible medical journalism?

This might be off topic a

This might be off topic a bit, but it relates, to a degree.
from CNN--
http://www.cnn.com/2009/US/06/24/us.airways.1549.claims/index.html#cnnST...
A Mrs. Sosa is complaing that in addition to getting her belongings back, in addition to having 3 mental therapy sessions for herself adn her family, in addition to getting 5K from U.S. Airways after the bird strike, and the perfect Sully landing, Mrs. Sosa wants the airline to pay and pay her more.

This is nuts. people see deep pockets and think why not soak everyone else. Nanny state people scare the hell out of me. They don't know when to stop asking for more.
This reminds me of Obama: What's another 10 trillion?

Obamacare will be nanystate care and taxpayers will pay through the nose for Mrs. Sosa and her ilk to get what she is "entitled" to get.

update: Mrs. Sosa has asked the airline for free hot fudge sundaes for life!

Just this evening on network

Just this evening on network news, I watched a report on new drug that goes after a specific gene mutation for breat cancer. I had just read this FS post and had an ahha moment.
Sure, I want fewer ppl to get sick, but I get it now. That means more of the same--the same telling us the same things. prevention is fancy talk repeating to us all the stuff we all read in Fitness or Self every month.

I read all the diet and health articles in women's magazines, and you're right, they all come down to eat right and hit the gym. I know obesity has very high rates in African Americans. Maybe that is why Obama is so bent on the prevention thing. But I live in the Midwest, and lots of lower middle class white folks here eat too much and think of stairs as emergency only. They all read Prevention magazine at the doctor's office, just like I do.

I know that the majority of Americans are overweight, but this just seems like more of Obama puttting penalty on those who do the right thing (in this case, exercise on reg basis, and eat good stuff) and rewarding those who may never do the right thing.
And yes, if I get cancer and need a treatment that is tailored to me, I will be mad as hell if no one has developed it so that the goverment post office health care can use all their money and effort to tell bad eaters to eat right. you are right! they already know this!

Lke you, I read this post and

Lke you, I read this post and immediately recalled a story I'd read in the New York Times about a week, ago. I cut it out to give to my neighbor who is caring a sick parent.
Here's a snippet:

"My father died last year at age 85. Over two decades, as his health declined, I cooked for him when I could.
It’s not that Dad had given up hope. Paradoxically, he loved life more as he grew sicker. And the happier he became, the more he indulged in things that were bad for his health.
Because his heart was failing, salty food made fluids pool in his body. But the soups he adored were oceans of sodium, prompting hospital visits and the need for powerful diuretics. Even while threaded with intravenous lines, he’d poke at his food and ask for salt from the cafeteria.

I made banana bread with yogurt and wheat germ, salmon with the barest suggestion of sauce. Dad received the food graciously, though I often returned to find it cached in the depths of the refrigerator, shriveled and rubbery. "
http://www.nytimes.com/2009/06/16/health/16case.html?_r=1&scp=1&sq=a%20t...

After reading this post, I started to think about all the savings Mr. Obama says we will wring out of health care by pushing preventions programs.

But humans are going to do exactly what this man did, eat what they like and expect the system to patch them back up. This man knew what was bad for him, but he'd decided to toss caution to the wind, eat all the bad things.
I suggest you read the whole story. It is a case study in the folly of expecting that if we spend trillions of dollars on prevention any real change will come about. Mr. Obama has no idea what he's talking about, just saying stuff that people want to hear. Prevention, yeah that sounds great: great for everyone else but me!

Who doesn't want hc reform?

Who doesn't want hc reform? But I don't want this Obama joker anywhere near it.
O's understanding of medical profession is zip. Sure, sure Obama, let's nationalize the system, and pay for it with digital health records. What a joke.
No one thinks Obama has a clue on how to do anything but spend 10 trillion bucks. When the government goes bust, and nanny state doesn't work how exactly will anyone get medicadl care?

And you are right, if Americans don't know by now what will keep them healthy, trillions more telling them won't help one iota. It is very much a poverty issue. We'd be better off going into a heathy fast-food franchise.

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